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Job Summary

  • Company

    Jiangyin Science and Technology Bureau​

  • Location

    Jiangyin/Shanghai/Wuxi Jiangsu, China​

  • Job Type

    Full Time

  • Salary Range

    Negotiable

  • Number to Recruit

    1

  • Job Reference Code

    J2200263

计算结构资深研究员

Jiangyin/Shanghai/Wuxi Jiangsu, China

About Company:

Wuxi Biortus bioscience Co., Ltd. was jointly founded in 2009 by Shuangliang group, one of the "top 500 Chinese enterprises", and a number of overseas scientists with working experience in foreign pharmaceutical industries. With its strong protein production and structural biology capabilities, the company has been providing global clients with new drug discovery services for SBDD (structure-based drug design).
Biortus has 4 technical platforms: protein expression & purification, biological assays, crystallography and cryoEM. In particular, with a total of 8 cryo-electron microscopes, Biortus is so far the largest one-stop cryoEM service provider in the world.
Led by Dr. Wu Jiaquan, the core team contains more than 10 overseas returnees. So far, a total of 19 scientific papers have been published in top journals such as 《Science》、《Nature》、《Cell》、《Cell Research》、《Nature Communications》、《Structure》、《Joumal of the American Chemical Society》etc. Biortus has about 220 employees, more than 50% of whom have a master's degree or above.
In last three years, Biortus has been maintaining more than 40% rising of annual sales revenue. Its clients includes many internationally renowned pharmaceutical enterprises and biotechs located in USA, Europe and Asia.
At Wuxi International Life Science Innovation Park, Biortus has built both "international cryoelectron microscope innovation center" and "international drug target protein innovation center" to implement the strategic plan "thousands of targets and thousands of seedlings" ®”. The goal of this plan is to deliver thousands of drug target proteins, tens of thousands of lead compounds, as well as their structure-activity relationship to global clients. Biortus is implanting the strategy of "new targets, new mechanisms and new molecules" into domestic pharmaceutical industries.


Job Profile:

生物/物理/化学/计算机相关专业


Job Details:

Responsibilities:

作为计算结构生物学部的重要成员,开展蛋白质建模、小分子虚拟筛选和生物大分子分子动力学模拟等工作
·收集和分析药物靶标蛋白信息,运用化学信息学手段寻找化合物
·负责基于片段的苗头化合物发现过
·参与设计和开发基于受体和基于配体的药物发现相关流程和算法
·与拥有丰富药物研发背景的其他核心技术团队合作,共同推动项目进展。


Qualifications:

·在生物、物理、化学、计算机等学科取得博士以上学历,1-3年以上相关工作经验
·具备同时处理多项任务的能力和一定的英语口语交流能力
·善于沟通交流,具备快速学习的能力
·对生物大分子有深入了解,欢迎有结构生物学或有机合成背景者应聘
·参与过计算机辅助药物设计相关课题者优先
·熟悉LINUX操作系统,有使用脚本语言或编程语言如Python等经验者优先。

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